The world is a mask that hides the real world.
That’s what everybody suspects, though the world we see won’t let us dwell on it long.
The world has ways - more masks - of getting our attention.
The suspicion sneaks in now and again, between the cracks of everyday existence…the bird song dips, rises, dips, trails off into blue sky silence before the note that would reveal the shape of a melody that, somehow, would tie everything together, on the verge of unmasking the hidden armature that frames this sky, this tree, this bird, this quivering green leaf, jewels in a crown.…
As the song dies, the secret withdraws.
The tree is a mask.
The sky is a mask.
The quivering green leaf is a mask.
The song is a mask.
The singing bird is a mask.


Wednesday, November 30, 2005

mouse brain online

Interactive 3-D atlas of mouse brain now available on web

UPTON, NY -- Researchers at the U.S. Department of Energy's Brookhaven National Laboratory have just launched a web-based 3-D digital atlas browser and database of the brain of a popular laboratory mouse (see http://www.bnl.gov/CTN/mouse/).

"Neuroscientists around the world can now download these extremely accurate anatomical templates and use them to map other data -- such as which parts of the brain are metabolically active and where particular genes are expressed -- and for making quantitative anatomical comparisons with other, genetically engineered mouse strains," said project leader Helene Benveniste, who is a researcher in Brookhaven's medical department and a professor of anesthesiology at Stony Brook University.



The database was created using high-resolution magnetic resonance (MR) microscopy at the University of Florida in collaboration with researchers from Brookhaven Lab's Center for Translational Neuroimaging. The work was done in parallel with an international collaboration, the Mouse Phenome Database (MPD) project, which was created to establish a collection of baseline phenotypic data from commonly used inbred mice.

The new brain atlas database consists of 3-D anatomical data from 10 adult male mice of the strain C57BL/6J, and contains data on 20 segmented structures, including variability of brain structures across the strain, and downloadable visualization tools.

The research that makes up this database was published as a cover article in the October 2005 issue of the journal Neuroscience.

###

This research was initially funded by the National Institute on Drug Abuse and then by the National Institute of Biomedical Imaging and Bioengineering (NIBIB). The development of the web-browser and database was supported by both NIBIB and the Office of Biological and Environmental Research within the U.S. Department of Energy's Office of Science. A variety of brain-imaging techniques including magnetic resonance imaging are a direct outgrowth of DOE's support of basic physics research.

One of the ten national laboratories overseen and primarily funded by the Office of Science of the U.S. Department of Energy (DOE), Brookhaven National Laboratory conducts research in the physical, biomedical, and environmental sciences, as well as in energy technologies and national security. Brookhaven Lab also builds and operates major scientific facilities available to university, industry and government researchers. Brookhaven is operated and managed for DOE's Office of Science by Brookhaven Science Associates, a limited-liability company founded by Stony Brook University, the largest academic user of Laboratory facilities, and Battelle, a nonprofit, applied science and technology organization. Visit Brookhaven Lab's electronic newsroom for links, news archives, graphics, and more: http://www.bnl.gov/newsroom


EurekAlert! Public release date: 30-Nov-2005

Contact: Karen McNulty Walsh
kmcnulty@bnl.gov
631-344-8350
DOE/Brookhaven National Laboratory






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